What are Mastocytosis?
The disease mastocytosis is characterized by having more number of mast cells than that required by the body in various organs and tissues. This is more common in skin. The commonest form of mastocytosis is urticaria pigmentosa and this causes round/ oval macules, plaques or papules of color red-brown. The children are affected to the maximum (75%) whereas people in the age group of 30 to 49 years are affected next. Mast cell is a connective tissue cell and it contains histamine, serotonin and heparin; these are reactions to allergy. Mast cells are useful for healing the wound. They also are supposed play some part in the blood vessels growth. For survival of human beings mast cells are required. If the quantum of mast cells is high mastocytosis occurs. If the mast cells are high on the skin then it is called cutaneous mastocytosis or urticaria pigmentosa whereas if it occurs in internal organs of the body it is known as systemic mastocytosis. What causes mastocytosis? Mastocytosis is
