What are internal controls and why are they necessary?
In scientific experiments, internal amplification controls (a.k.a. internal controls) are used to eliminate alternate explanations for outcomes and validate the integrity of the results. In a diagnostic test, an internal control is an unaltered result used as a standard against which actual results are compared. Having an internal control helps to eliminate errors and bias, and ensures that the test is working as expected. “The European Standardization Committee, in collaboration with International Standard Organization (ISO), has proposed a general guideline for PCR testing that requires the presence of Internal Amplification Control in the reaction mixture.” All AnDiaTec tests, including BoVir®, are performed using internal controls for optimum accuracy.
