What are important differences between fat- and water-soluble vitamins?
Fat soluble vitamins can become toxic because they are stored in fat tissue and liver, whereas water-soluble vitamins are readily excreted in urine and stored in small amounts only, not reaching toxic levels. 3. What are the important roles of thiamine (B1)? A: It is present in thiamine pyrophosphate, a cofactor in decarboxylation reactions, using a single reactive carbon. It is important in energy metabolism. Deficiency results in beri-beri or Wernicke-Korsakoff syndrome (associated with alcoholism). 4. What are the important roles of riboflavin (B2)? A: It is used in cofactors: FMN (flavin mononucleotide), FAD (flavin adenine dinucleotide) in flavoenzymes to catalyze redox reactions. Reduced forms: FMNH2 and FADH2. 5. What are the important roles of niacin? A: It is used in cofactors: NAD+ (nicotinamide adenine dinucleotide), NADP+ (nicotinamide adenine dinucleotide phosphate) in redox reactions. Reduced forms: NADH and NADPH. It can be obtained in limited amounts by metabolism of tr
