What are Hyperplastic and Sessile Serrated Polyps?
Hyperplastic polyps are not an uncommon polyp, and are often routinely found during colonoscopy screening. The importance of the hyperplastic polyp as a precursor for colorectal cancer has not been well studied, though most evidence indicates that hyperplastic polyps are not generally associated with colorectal cancer. Hyperplastic polyps are generally thought to be truly benign growths, possessing no potential for progression to colorectal cancer. Contrast this with the adenoma, the colon polyp strongly associated with colorectal cancer, fewer than 10% of all adenomas become cancerous, however, more than 95% of colorectal cancers develop from adenomas. Hyperplastic polyps share similar features to a related polyp known as a sessile serrated adenoma. Sessile serrated adenomas are related to hyperplastic polyps, but have dysplasia, this feature makes it more likely for a sessile serrated adenoma to progress to colorectal cancer than hyperplastic polyps. While hyperplastic polyps are sim