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What are Gastrinomas, where they often occur ?

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What are Gastrinomas, where they often occur ?

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Gastrinomas are tumors characterized by secretions of large amounts of gastrin, a hormone that increases the amount of acid released by the stomach. Gastrinomas are most commonly associated with Zollinger-Ellison syndrome (ZES) (ZES), a rare gastroenterological disorder. This disorder is more commonly referred to as peptic ulcer disease and is also sometimes called gastrinoma because of its close association with gastrinomas. Gastrinomas most often occur in the duodenum and the pancreas, though they may also occur in the pituitary gland and the hyperfunction of the parathyroid gland. About 66% of gastrinomas are malignant, often spreading to the patients liver.

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