What are disadvantages of current FMDV vaccines?
The current FMDV vaccines are killed virus vaccines, and they can be hazardous due to contamination by live viruses in the manufacturing process. Vaccination can lead to a serological pattern that is very similar to natural infection, so it is difficult to tell the difference between infected and vaccinated animals by serum assays. Current FMDV vaccines only offer narrow protection, the virus used in vaccine has to closely resemble the virus in circulation. UBI solution: The UBI FMDV vaccine is a synthetic subunit vaccine. No virus is used in its manufacturing, so it is absolutely safe. The UBI synthetic FMDV vaccine triggers a serological response that is very different from the one induced by natural infections, so it can facilitate serological surveillance of natural infections. The UBI designer synthetic vaccine offers broader cross protection against a wider range of virus strains. More importantly, in this age of genomics, we can quickly synthesize designer vaccines according to