What are biologic agents and how do they work?
Researchers now know that psoriasis is an immune-mediated disease involving T-cells. Scientific investigation on how to reduce these psoriasis-causing immune cells and stop the chemicals that the T-cells release represents one focus of current psoriasis research. Biologic agents are usually used for people who have failed to respond to (or cannot use) traditional therapies (such as vitamin D derivatives and steroids), older, systemic therapies or for people with associated psoriatic arthritis. These biological therapies use a specific, targeted approach to interrupt the underlying immune-mediated processes that drive psoriasis.