What are ALT (SGPT) and AST (SGOT)?
A. AST (SGOT)- this enzyme has its highest concentrations in the heart, liver, and muscles. Increased levels in the blood are seen shortly after a heart attack, in liver disease and diseases involving muscle damage. Reference range is 7-56 U/L. ALT (SGPT) – this enzyme is present in higher concentrations in the liver than muscle. Consequently an elevation is more specific to liver disease. Both SGOT and SGPT become elevated whenever liver cells are damaged. Reference range is 7-56 U/L. We have never seen any change in these enzymes in all of the Cholestin studies we have done, but there is always a chance. That is why the following warning appears on the label – “Cholestin contains several natural HMG-CoA reductase inhibitors, one of which has been associated with rare (in less than 1 to 2% of users) but serious side effects. DO NOT take Cholestin if: you are at risk of liver disease, have active liver disease or any history of liver disease; you consume more than 2 drinks of alcohol p