What advantages does the qNPA ArrayPlate have over other miRNA technologies?
No RNA Extraction qNPA based technologies use a simple lysis step to obtain the RNA for analysis, not an expensive, time-consuming, and artifact-introducing RNA extraction procedure. This not only simplifies the workflow of gene expression analysis, but it also reduces the amount of noise introduced in to the data measurements. qNPA measures the changes in gene expression due to biology, not the choice of RNA extraction technique. Sensitivity The qNPA ArrayPlate platform will routinely detect as few as 15,000 miRNA molecules in a sample well. With a typical sample size of 15 to 25 thousand cells, we can reliably detect a miRNA present at one transcript per cell. The no-amplification nature of the qNPA System ensures that signal is not obtained due to amplification artifacts. Selectivity Spurious signal due to cross-hybridization of closely related sequences is minimal in the ArrayPlate, unlike other technologies. Two closely related miRNAs were tested on the qNPA ArrayPlate and a leadi
