We manufacture hundreds of different products for food packaging. To test every combination is of course unaffordable – what is an appropriate sampling plan under this scenario?
I am unable to give a general answer to this “practical” case. I can just recommend to compile all the data available for the materials and substances and look out for the worst cases, perhaps by using modelling programs, such as migrapass, migratest, multiwise etc. Literature research and consultation of FDA data bank on migration data could be also useful.
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