There are two graphs in the bioequivalence study. What do they mean?
The Linear Plot-Time versus Plasma Concentration Graph and the Semi-Log Time versus Plasma Concentration are essentially the same. The graphs represent the peak and troughs of both the reference drug and our brand in the system (bioavailability). The Y axis demonstrates plasma concentration and the X axis is the duration. Notice that on the initial phase of the drug intake, the blood levels of our drug (e.g. Amlodine) and the reference drug (e.g. Norvasc) rises at the same pace. This is true for the succeeding hours which demonstrate the clearance and elimination of the medicine.
