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The RFA excludes applications focusing solely on animal studies. Can human lung expression signatures be validated or otherwise studied from a mechanistic perspective in animal models of lung disease?

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The RFA excludes applications focusing solely on animal studies. Can human lung expression signatures be validated or otherwise studied from a mechanistic perspective in animal models of lung disease?

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We strongly discourage the use of animal models under this RFA. Having a large volume of gene expression data from human subjects is critical for the subcategorization study of lung disease. The application should be fully focused on human subjects.

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