The Echo systems transfer fluids into plates that are upside down! Won’t the fluids drain out?
For nanoliter droplets, surface tension is a much stronger force than gravity. In high-density plates the liquid is held tightly even when there are microliters of fluid in each well. Try the experiment yourself: put liquid into each well of a multi-well plate and turn it upside down. You will have to vigorously shake the plate or hit it on a table to knock the liquid out of the plate. Back to main list.
