The ‘bioaccessible fraction’ has changed to ‘relative bioavailability’ in the CLEA software v1.06, is the data that I previously used for arsenic incorrect?
We have replaced the bioaccessibility factor with the relative bioavailability factor and the description in the software and handbook amended accordingly. While the descriptive text has been amended, the way that the model applies this factor has not changed from the previous version (that is, version 1.04). Bioaccessibility and relative bioavailability are terms that have been commonly used interchangeably. In general this is incorrect as the two terms do not share the same definition. However, in the particular case of arsenic the mathematical relationship between the two parameters can be simplified to demonstrate that they are approximately equivalent.
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- The ‘bioaccessible fraction’ has changed to ‘relative bioavailability’ in the CLEA software v1.06, is the data that I previously used for arsenic incorrect?
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