Temporal arteritis. What is the worst thing that can happen if untreated?
Giant cell arteritis involves predominantly the thoracic aorta, large arteries emerging from the aorta in the neck, and extracranial branches of the carotid arteries. Simultaneous polymyalgia rheumatica is common. Focal symptoms and signs may include headaches, visual disturbances, temporal artery tenderness, and pain in the jaw muscles during chewing. Fever, weight loss, malaise, and fatigue are also common. ESR and C-reactive protein are typically elevated. Diagnosis is clinical and confirmed by temporal artery biopsy. Treatment with high-dose corticosteroids and aspirin is usually effective and prevents visual loss.