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Sometimes we see swelling at the site of injection when giving Td. Will giving Tdap before a five year interval increase the incidence of swelling?

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Sometimes we see swelling at the site of injection when giving Td. Will giving Tdap before a five year interval increase the incidence of swelling?

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It is possible when tetanus- and diphtheria-containing vaccines are given close together for the person to experience an increased local reaction (redness, tenderness, and swelling) at the site of injection. However, it is a risk benefit situation. If there is a risk of pertussis infection or transmission, then it would seem that the benefit of vaccination against pertussis would outweigh the potential for a sore arm.

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