Important Notice: Our web hosting provider recently started charging us for additional visits, which was unexpected. In response, we're seeking donations. Depending on the situation, we may explore different monetization options for our Community and Expert Contributors. It's crucial to provide more returns for their expertise and offer more Expert Validated Answers or AI Validated Answers. Learn more about our hosting issue here.

Since Size Exclusion is not used in large scale process what alternatives are availble?

April 26, 2017Alternatives availble exclusion large process scale size Used

0

10 Posted

Since Size Exclusion is not used in large scale process what alternatives are availble?

1 Answer

0

10 Posted

Tosoh Bioscience often recommends using HIC as a attractive alternative to SEC. Although HIC does not have the binding capacity of IEC, it is quite powerful at separating isoforms of the protein (such as aggregates and misfolded species) that may not be resolvable on ion exchange resins.