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Since finasteride inhibits only the Type 1 5-alpha reductase, how do you know that the serum DHT is decreased with the use of topical finasteride?

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Since finasteride inhibits only the Type 1 5-alpha reductase, how do you know that the serum DHT is decreased with the use of topical finasteride?

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A. Independent studies from other researchers (e.g. Rushton and Ramsay in an article in the British Journal of Medicine) have shown that topical finasteride lowers the serum by inhibiting the synthesis of DHT in the prostate. “A 0.05% formulation of topical finasteride was well absorbed and lowered the serum dihydrotestosterone concentration by up to 40%”.

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