Shouldn I worry about “rejection” or some type of immune response when tissue from another animal is transplanted?
No, because the cells with surface markers that stimulate an immune response are removed through our processing. Osteoallograft is composed of bone. Tissues which may contain immunogenic cells (periosteum, synovium, etc.) are removed during the early part of processing. Any marrow-containing bone is also purged of living cellular materials. As in human medicine, when bone grafts are used for surgeries no matching of tissue type or blood groups is necessary.