Should women stop taking estrogens and progestins for cardiovascular protection?
Estrogens and progestins have never been FDA-approved for heart attack prevention. The FDA has not allowed any claims about benefits for prevention of heart disease. Now, the WHI study findings clearly show an increased risk for heart attack and stroke in women. Women should not take estrogens and progestins to prevent heart attacks or stroke. FDA recommends that women talk to their doctor about other medications or lifestyle measures (such as smoking cessation) to reduce the risk of heart attacks. 19. What does this mean for use of estrogen alone? (4/19/2004) The estrogen alone substudy of the WHI was stopped by NIH on March 1, 2004 because estrogen alone does not appear to affect (either increase or decrease) heart disease in postmenopausal women without a uterus. At the same time, estrogen alone appears to increase the risk of stroke, decrease the risk of hip fracture, and it has not increased the risk of breast cancer after a mean of 6.8 years of follow-up. There are other side eff
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