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Should Rh (D) immunoglobulin be given for first trimester bleeds that do not result in miscarriage?

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Should Rh (D) immunoglobulin be given for first trimester bleeds that do not result in miscarriage?

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The NHMRC Report (2003) states that there is insufficient evidence to support the use of Rh (D) immunoglobulin in bleeding prior to 12 weeks’ gestation in an ongoing pregnancy, although if the pregnancy then requires curettage Rh (D) immunoglobulin should be given. If the bleeding is particularly heavy or associated with a visible subchorionic haemorrhage these patients should be considered at higher risk of sensitisation and Rh (D) given.

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