Should pregnenolone be used together with DHEA?
Many on the forefront of anti-aging research are advocating the use of both pregnenolone and DHEA, both in low doses. 15 mg to 25 mg each of pregnenolone and DHEA seems to do the trick in many women to bring them a renewal sense of well-being. Men are less hormone sensitive and the results may not be as evident. For men, direct testosterone precursors such as androstenedione ( and its metabolite androstenediol ) may be more effective. Are there any drug interactions between DHEA and prescription medications? Since DHEA is a slight mood elevator, it could potentially clash with anti-depressants. Theoretically, the dosage of anti-depressants could be lowered if DHEA is taken. People on cholesterol lowering drugs as well as blood thinning medications, such as coumadin, may need to watch their medications, as well as the requirements, because these may well be reduced since DHEA has both a cholesterol lowering and blood thinning effect. Studies have shown that DHEA also reduces appetite, s