Should patients with atrial fibrillation take Sumatriptan for migraines?
Those who have atrial fibrillation should not be taking the triptan class of medications such as sumatriptan (Imitrex). Any person who has a prior history of heart condition should reconsider taking these drugs, but in clinical trials – the only people who had atrial fibrillation from the medication, were the ones who had a prior history of it. So, taking these medications can trigger this arrhythmia in those who already suffer from it.