Should ObGyns consider Botox for women with intractable symptoms?
For clinicians experienced with cystoscopically guided injections, Botox might be a reasonable option for highly selected women who are truly refractory to all other treatments for detrusor overactivity incontinence. Such women should understand that Botox is not FDA-approved for this indication and that its use is experimental. No evidence identifies the optimal dose of Botox to be injected cystoscopically for incontinence related to detrusor overactivity. However, dosing information may be forthcoming from a Phase II study being performed by the company that markets Botox (Allergan).
