Should MATra be processed in serum-free medium?
It is one of the great benefits of the method that the presence of serum does not interfere with MATra. Only the incubation with nucleic acid and MATra-A Reagent or MA Lipofection Enhancer should be done in a medium free of serum or supplements. Serum and supplements could interfere with the assembly of the nucleic acid and the magnetic nanoparticles. Subsequent transfection via MATra is, however, not affected by serum or supplements and can thus be performed in their presence.
