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Should magnesium sulfate be used for fetal neuroprotection?

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Should magnesium sulfate be used for fetal neuroprotection?

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The author ponders the potential of magnesium sulfate to provide fetal neuroprotection and prevent cerebral palsy (CP). Investigators believe neuroprotection is possible through reduced vascular instability and hypoxia-reperfusion injury and/or reductions in cytokine- or excitatory amino acid-induced damage. Studies showing the ability of magnesium sulfate treatment to prevent CP are cited. Also explained are reasons why caution should be exercised in introducing such treatment.

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