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Should liver metastases of breast cancer be biopsied to improve treatment choice?

April 26, 2017biopsied breast cancer liver metastases treatment

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Should liver metastases of breast cancer be biopsied to improve treatment choice?

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M. A. Locatelli, G. Curigliano, L. Fumagalli, V. Bagnardi, G. Aurilio, P. Della Vigna, L. Monfardini, S. Giudici, G. Viale and A. Goldhirsch Division of Medical Oncology, European Institute of Oncology, Milan, Italy; Division of Epidemiology and Biostatistics, European Institute of Oncology, Milan, Italy; Division of Radiology, European Institute of Oncology, Milan, Italy; Division of Pathology, European Institute of Oncology, Milan, Italy; International Breast Cancer Study Group, Bern, Switzerland Abstract CRA1008 Background: Decision making on systemic treatment of women with metastatic breast cancer is based on features like estrogen receptor (ER), progesterone receptor (PgR), and HER2 status assessed on the primary tumor. We evaluated the concordance of receptor status between primary tumor and liver metastases (mts) and its impact on treatment choice. Methods: We retrospectively analyzed a database including ultrasound guided liver biopsies performed from 1995 to 2008. All tissue