should growth hormone deficiency in older people Be treated?
Lieberman SA – Clin Geriatr Med – 1997 Nov; 13(4): 671-84 From NIH/NLM MEDLINE, HealthSTAR NLM Citation ID: 98022838 Full Source Title: Clinics in Geriatric Medicine Publication Type: Journal Article; Review; Review, Tutorial Language: English Author Affiliation: Division of Endocrinology, Department of Internal Medicine, The University of Texas Medical Branch, Galveston, Texas, USA. Authors: Lieberman SA; Hoffman AR Number of References: 47 Abstract: Secretion of growth hormone (GH) by the pituitary gland progressively declines beginning in early adult life, a phenomenon which is termed “the somatopause.” The observation that many of the changes which occur with advancing age are opposite to the physiologic effects of GH suggests that declining levels of GH and insulin-like growth factor I (IGF-I), the mediator of many of the actions of GH, may be responsible for some of these changes. This article reviews the current understanding of mechanisms underlying the somatopause, the changes
