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Should adjusted or unadjusted estimated GFR be used when dosing medications?

April 26, 2017Adjusted dosing estimated gfr medications unadjusted Used

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Should adjusted or unadjusted estimated GFR be used when dosing medications?

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Drug dosing is based on kidney function measurements or estimates that are not adjusted for body surface area. GFR estimates adjusted for body surface area will generally be adequate except in patients with body size that is very different than average. In these patients, unadjusted estimated GFR can be computed by the following formulas: BSA = W0.425 x H0.725 x 0.007184 /1.73 m2 GFR estimate (mL/min) = GFR estimate (mL/min/1.73 m2) x BSA/1.