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Saliva testing measures the free or bioavailable fraction of hormone. Does blood spot testing measure the same thing?

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Saliva testing measures the free or bioavailable fraction of hormone. Does blood spot testing measure the same thing?

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Blood spot testing measures the total amount of hormone available to tissues, but when divided by the amount of SHBG, this ratio then determines how much of the hormone is bioavailable. So, by combining estradiol or testosterone with SHBG testing, it is possible to determine the bioavailable fraction of these hormones indirectly. This is why we included the SHBG test in our Female and Male Hormone Profiles in Blood Spot.

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Blood spot testing measures the total amount of hormone available to tissues, but when divided by the amount of Sex Hormone Binding Globulin (SHBG), this ratio then determines how much of the hormone is bioavailable. So, by combining estradiol or testosterone with SHBG testing, it is possible to determine the bioavailable fraction of these hormones indirectly. This is why we included the SHBG test in our Female and Male Hormone Profiles in Blood Spot.

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