Restylane and Botox Q: What is the difference between Restylane and Botox?
I get this question a lot lately. Restylane is a sugar derivative used to plump up creases in the skin of the face. It is best for the lower third of the face (lip lines, naso-labial folds and marionette lines). The injection is painful so a numbing block is given around the mouth (like at the dentist) to make the procedure more comfortable. Some swelling may occur in the lips for 24-48 hours.