premenopausal woman need progesterone cream?
In the ten to fifteen years before menopause, many women regularly have anovulatory cycles in which they make enough estrogen to create menstruation, but they don’t make any progesterone, thus setting the stage for estrogen dominance. Using progesterone cream during anovulatory months can help prevent the symptoms of PMS. We now know that PMS can occur despite normal progesterone levels when stress is present. Stress increases cortisol production; cortisol blocks (or competes for) progesterone receptors. Additional progesterone is required to overcome this blockade, and stress management is important.
