Prednisone [posted 7/30/98] Question: I am curious as to how prednisone causes a decrease in inflammation. Biochemically, how does this drug work?
It appears that they inhibit specific functions of white blood cells. This limits the production of factors necessary to initiate and continue the inflammatory response. This includes inhibition or decreased production of histamine, leukotriene, cytokines, arachidonic acid byproducts, and different acute phase reactants. This occurs in basophils, fibroblasts, lymphocytes, macrophages and endothelial cells. Prednisone and Cataracts [posted 7/27/98] Question: I was looking for information on prednisone. I need to take this medication for arthritis pain. I also take daypro 1200 mg each day. I now have the first stages of cataracts in both eyes. I am taking only 6 mg of prednisone I have been up to 35 mg when I was in more pain. Is there any information on how fast eye problems progress? Answer: Everyone is different, but it will speed up cataracts – depending on your current age and your history of family cataracts. It is dose and time dependent. This means use as little as possible for a