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PAXgene® Blood RNA Tubes are breaking after I freeze the tubes at -80°C. Why?

April 26, 2017blood breaking freeze paxgene® RNA tubes

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PAXgene® Blood RNA Tubes are breaking after I freeze the tubes at -80°C. Why?

1 Answer

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Do not store and freeze tubes upright in a styrofoam tray as this may cause tubes to crack. Store and freeze tubes upright in a wire rack. If tubes are to be kept at -80°C, freeze them first at -20°C for 24 hours, then transfer them to -80°C.