on a constant basis. 4.4: How bioavailable is creatine?
creatine is unknown. Some creatine is degraded to creatinine in the GI tract, but the amount is probably low (one study estimated about 2%). It is believed that it is actively transported in the intestine by a saturable transporter. As the dosage of creatine increases, the time to maximal concentration and half-life increase. High doses, such as 20 g, cause an increase followed by a plateau in blood creatine levels lasting about six hours before dropping. The main limiting factor for muscle creatine uptake is the creatine transporter. This transporter is highly selective for creatine. Another naturally occuring compound, beta-guanidinopropionic acid, also competes for the creatine transporter. As levels of creatine in muscle tissue increase, the creatine transporter downregulates. This makes it so muscle tissue can only store a certain limited amount of creatine. Although this amount is not maximized in most individuals not supplementing with creatine, the limiting role of the creatine
Related Questions
- Unfortunately this does pose a problem as we are in constant contact with out clients by email, should you not have access to email on a daily basis, it is regrettable, but we would have to decline your order with us. What is the difference between this and other photo painting sites?
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