My timing between doses of dDAVP varies. For the nasal spray it can vary from 6 hours to 18 hours. * Does my pituitary gland sometimes produce a small amount of the hormone, even if I have CDI?
In some patients with CDI, the pituitary is able to produce small amounts of the hormone as, for example, when they smoke or become dehydrated. However, the variability in the duration of action of the dDAVP in you is probably due mainly to variability in the efficiency of adsorption. Colds, sinusitis, or even a little hay fever markedly impair the absorption of the drug from the nasal mucosa and result in much shorter durations of action.
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