My thyroglobulin blood test was measured at the time I received my radioactive iodine-does this have any prognostic significance?
The thyroglobulin level is a indirect assessment of how many thyroid cells remain, since it is only thyroid cells that can produce thyroglobulin. Several studies suggest that the lower the level of thyroglobulin even prior to treatment with radioactive iodine, the lower the risk of recurrence. For example patients with a thyroglobulin of less than 2 ug/ml after thyroid surgery have a very low risk of disease recurrence, as described in Serum Thyroglobulin Levels at the Time of 131I Remnant Ablation just after Thyroidectomy are Useful for Early Prediction of Clinical Recurrence in Low-risk Patients with Differentiated Thyroid Carcinoma. J Clin Endocrinol Metab. 2004 Dec 21; [Epub ahead of print].
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