My child has a positive throat culture. Should I also have tests for ASO or Anti-DNAseB?
We\’d recommend against it. The unfortunate reason is that some doctors think that if your ASO comes back negative you can\’t have PANDAS. That is not true. ASO has a 46% false-negative rate. That\’s almost the same as a coin flip. If you have a positive throat culture, treat it. If it is associated with significant exacerbation, PANDAS is probable.