Montrose Q: Antibodies vs. dendritic cells: Are antibodies only activated in disseminated infections and dendritic cells activated in localized infections?
Dendritic cells get activated in local infections and, if the disruption is strong enough (technically, if the local cells release enough cytokines and chemokines) the dendritic cell will leave the area, go to the nearest lymph node, and show what its seen to the T and B cells there, resulting in a systemic immune response.
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