Molecular Nano Tagging — Is it Large Enough?
As we progress in understanding of living systems and their underlying nano- and subnano-scale molecular principles, the scientific methodologies and tools for investigations tend to rely more on indirect observations with a significant amount of uncertainty, generating more questions than answers. As results of the attempts to define the complex behaviors and patterns of nano-scale interactions between organic and inorganic materials by taking advantage of the recent advances in computational powers and nano-scale chemical processing, we developed a molecular signaling agent based on self-contained Surface Enhanced Raman Scattering. The exact conformations and electrochemical interactions on the surface of nano-aggregates are still mostly in speculations, but the semi-empirical engineering to manipulate and configure such molecules into “right” sizes to produce optically strong signals appears to become largely under control, leading to a development of highly sensitive, high-resoluti