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Might topiramate be effective in people who have failed to receive benefit from other psychopharmacologic agents?

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Might topiramate be effective in people who have failed to receive benefit from other psychopharmacologic agents?

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The major use of topiramate in psychiatry is with people who have mood disorders that have not been adequately controlled by other medications at times including lamotrigine and gabapentin. A developing use is for people with PTSD. Topiramate has also been shown to decrease craving for alcohol in people with alcoholism, and to prevent migraine headaches.

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