May I vaccinate a puppy that is at high risk of getting CDV with a human measles vaccine?
No – Due to an insufficient amount of virus, the human MV vaccine is not immunogenic in the puppy. Measles virus vaccines made specifically for the dog (sometimes combined with CDV) will give temporary protection at an earlier age than a CDV vaccine. At 16 weeks or older, the puppy must be vaccinated with a CDV vaccine, to achieve permanent immunity. 26. I know that maternally derived antibodies (MDA) can prevent active immunization with MLV vaccines – but can they also block immunity to killed vaccines? Yes – MDA can indeed block certain killed vaccines. If the killed product requires two doses, as is often the case, and the first dose is blocked by MDA, then the second dose will not immunize. In this circumstance, the second dose will prime (if not blocked), and a third dose is required to boost and immunize. This is not true for MLV, where – in the absence of MDA – it only takes a single dose to prime, immunize, and boost. Nevertheless two doses are often recommended, particularly i
