May I use more Periogen than the label says?
Answer Yes. The amount of Periogen® to use as indicated in the directions is meant to ration the bottle for the maximum amount of applications. There is no limit to how much you can use for a given application. Periogen® anti-tartar effectiveness may increase slightly by adding more, but will make little difference in the long run. Since Periogen® is effervescent by nature, adding more for application via a periodontal applicator may introduce a momentary discomfort.