Management of wound infection after appendectomy: are parenteral antibiotics useful?
Author(s): Harahsheh B, Hiyasat B, Abulail A, Al-Basheer M Affiliation(s): Department of Surgery, King Hussein Medical Centre, Royal Medical Services, Amman, Jordan. Publication date & source: 2002-07, East Mediterr Health J., 8(4-5):638-44. Publication type: Clinical Trial; Randomized Controlled Trial This study investigated the use of antibiotics in the treatment of wound infections after appendectomy. The subjects were 72 patients with post-operative wound infections at a district general hospital in Jordan. All patients received daily antiseptic dressings with povidone-iodine 10% in alcohol. The patients were randomized in a single-blind trial to receive either no antibiotics or parenteral antibiotics metronidazole and cefoxitin. There was no significant effect of antibiotic use in patients with early inflamed or severely inflamed appendicitis. However, for patients with perforated appendicitis the mean length of hospital stay and the mean frequency of change of dressings were sign