Ive had the iron profile tests, read them myself and they were within the normal range; do I need to be retested ever again and/or have the DNA genetic test, especially since I feel fine?
Yes. Even if your first test was negative, ideally, you should be monitored annually by your physician. Also, by having the DNA test, you can discover if you have the single or double gene for hemochromatosis and determine your risk factor of developing full blown hemochromatosis or passing a mutation to offspring. A very small percentage (about 12% to 15%) of patients who are clinically iron overloaded (have high TS and serum ferritin levels) may have a negative result on the genetic test. Scientists believe that these persons have still another HH mutation (which has yet to be discovered and a test for it developed) which is causing this iron storage. For this reason, it is always wise to test using the transferrin saturation and serum ferritin annually to be on the safe side.
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