Is vitamin A playing a hidden role in childrens lung function?
Fernando Sempértegui Corporación Ecuatoriana de Biotecnología, Department of Immunology, Universidad Central del Ecuador, Escuela de Medicina, Av. Colón, 1485 y nueve de Octubre, of. 202, Quito, Ecuador. Kassaye et al.1 have evaluated for the first time the relationship between vitamin A status and respiratory function in children. Previous studies in adults suffering from chronic diseases, which affect respiratory function, have shown a beneficial effect of short-term vitamin A supplementation on forced expiratory volume (FEV1) and/or forced vital capacity (FVC). Because vitamin A deficiency is associated with keratinizing metaplasia of the respiratory tract in children, the authors hypothesized that the differential vitamin A status of malnourished children could be related to differential FEV1 and FVC values. Measurement of FEV1 and FVC in children is difficult because it requires good co-operation from each child and the authors enrolled children of 6 9 years. Moreover, FEV1 and FV
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