Is venlafaxine toxic if an overdose is taken?
Fourteen overdoses of venlafaxine have been reported. In some cases venlafaxine was taken along with alcohol and/or other medications. All individuals who took an overdose recovered without sequelae. • What precautions are necessary when switching between venlafaxine and an MAO inhibitor? When switching from an MAO inhibitor to venlafaxine, there should be a 14-day interval between the discontinuation of the MAOI and the initiation of venlafaxine therapy. When switching from venlafaxine to an MAOI, a 7-day interval is adequate because of venlafaxine’s short half-life. • What does venlafaxine cost? Venlafaxine is supplied in tablets ranging from 25 to 100 mg in strength. The 25 mg tablets cost pharmacies nearly as much as the 100 mg tablets ($0.71 vs. $0.83). It is expected that all strengths of venlafaxine will be sold for between $1.00 and $1.50 per tablet. • Might venlafaxine be effective when a person has not responded to other antidepressants? In patients who have not responded to
