Is vascular tissue subject to growth after microtrauma,the way muscle tissue is?
Regulation of microvascular function is associated with endothelial cells at the blood-tissue interface. This cell layer is responsible for the smooth muscle tone of vascular tissues and their response to injury. Endothelial cells synthesize and interact with hormones and mediators through complex inter and intra cellular signaling pathways. One example of such a molecule is vascular endothelial growth factor (VEGF). It is a polypeptide that stimulates the growth of endothelial cells and promotes the growth of blood vessels. Endothelial cells have surface receptors for VEGF. And that is just one of the interactions that leads to vascular tissue repair. You can imagine all of the “helper” molecules that affect each pathway! I know that dietary copper plays a role in vascular resistance and smooth muscle reactivity, but I am not familiar with the putative use of L arginine alpha ketoglutarate (the essential aa, arginine and the citric acid cycle intermediate, AKG) for boosting nitric oxi
