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Is TWA exposure the appropriate metric?

appropriate exposure metric twa
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Is TWA exposure the appropriate metric?

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The epidemiological studies carried out so far have tended to use TWA exposure as the most robust metric because of the absence of a plausible biological mechanism for adverse health effect at environmental levels. However other metrics, such as peak values, time above thresholds, number of excursions and presence of transients, may be investigated in future studies.

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