Is titanium dioxide safe?
TiO2 used as photocatalyst is physically and chemically safe. The US certified it as a food additive in 1968 and Japan did it in 1983. It is now used widely in making white chocolates and functional cosmetics, including lipsticks. The Food Analysis Center of Japan Food Research Laboratories and Mitsubishi Chemical Safety Institute Ltd. demonstrated its safety through skin simulating tests and acute oral toxicity test.